bisphenol a epoxy resin chemical formula

FDA will update its assessment of BPA and will take additional action if warranted. Found that primates (including humans) of all ages effectively metabolize and excrete BPA much more rapidly and efficiently than rodents. The chemical formula of Bisphenol A isC15H16O2. Bisphenol A is a chemical compound containing two phenol functional groups. BPA is one of the most thoroughly tested chemicals in use today and has a safety track record of more than 50 years. According to the ratio of raw materials, the reaction conditions and adopt the same method can be obtained with different degrees of polymerization of low molecular weight viscous liquid and high . Some are conducted according to internationally recognized standards that ensure methodological and statistical reliability, and others are not. As is the case when foods are in direct contact with any packaging material, small, measurable amounts of the packaging materials may migrate into food and can be consumed with it. Toxicol Lett. Epoxy is a synthetic resin that uses two chemical components (typically diglycidyl ethers and a combination of bisphenol A and epichlorohydrin) to harden or cure. If youve ever read a news article or blog post about chemicals, you may have heard the oft-cited claim that there are 84,000 chemicals in commerce but only 200 of these have been tested for safety. Based on FDAs ongoing safety review of scientific evidence, the available information continues to support the safety of BPA for the currently approved uses in food containers and packaging. Usage: Industrial. Product. Toxicol Appl Pharmacol. It is found in various products including shatterproof windows, eyewear, water bottles, and epoxy resins that coat some metal food cans, bottle tops, and water supply pipes. Thanks to their high strength, versatility, and excellent adhesion to a variety of surfaces, epoxy resins have gained wide acceptance in diverse applications (coatings, electrical, casting resins, composites, etc.). .mw-parser-output .ib-chembox{border-collapse:collapse;text-align:left}.mw-parser-output .ib-chembox td,.mw-parser-output .ib-chembox th{border:1px solid #a2a9b1;width:40%}.mw-parser-output .ib-chembox td+td{width:60%}, Bisphenol A (BPA) is a chemical compound primarily used in the manufacturing of various plastics. Because of these attributes, polycarbonate is used in a wide variety of common products including digital media (e.g., CDs, DVDs), electrical and electronic equipment, automobiles, sports safety equipment, reusable food and drink containers, and many other products. Diglycidyl ether of bisphenol A epoxy resin (EPOLAM 2017), and 3-minomethyl-3,5,5 trimethylclohexylamine hardener (EPOLAM 2018). The National Institute of Environmental Health Sciences (NIEHS) is expanding and accelerating its contributions to scientific knowledge of human health and the environment, and to the health and well-being of people everywhere. While air, dust, and water are other possible sources of exposure, BPA in food and beverages accounts for the majority of daily human exposure. Developmental treatment with bisphenol A or ethinyl estradiol causes few alterations on early preweaning measures. Toxicol Appl Pharmacol. 80-05-7 Bisphenol a with Wholesale Price Min. Reports indicate that it is a minor skin irritant as well, although less so than phenol. The study orally dosed pregnant rodents with 100-1000 times more BPA than people are exposed to through food, and could not detect the active form of BPA in the fetus 8 hours after the mother's exposure. Health concerns have also been raised about these substitutes. Our line of powerful Liquid Epoxy Resins -including Bisphenol A, Modified Bisphenol A, Bisphenol A/F, Modified Bisphenol A/F, Bisphenol F offers the reliability, protection and performance you need, backed by the local customer support Only Olin can provide, virtually anywhere in the world. Scientific studies show that in humans BPA is quickly metabolized and eliminated from the body. To address these questions the National Toxicology Program, partnering with FDAs National Center for Toxicological Research is carrying out in-depth studies to answer key questions and clarify uncertainties about BPA. In July, 2012, FDA took this action in response to a food additive petition filed by the American Chemistry Council (ACC) [9]. Bisphenol A is the chemical product of combining one acetone unit with two phenol groups. Bisphenol A (BPA) is a chemical building block that is used primarily to make polycarbonate plastics. Bisphenol A can leach into food from the protective internal epoxy resin coatings of canned foods and from consumer products such as polycarbonate tableware, food storage containers, water bottles, and baby bottles. [21] BPA has been investigated by public health agencies in many countries, as well as by the World Health Organization. Bisphenol-A Based Epoxy Vinyl Ester Resins Home Bisphenol-A Based Epoxy Vinyl Ester Resins VE resins are a combination of both polyester resin and epoxy resins best properties. Epoxy resins are typically formed by the reaction of compounds containing at least two active hydrogen atoms (polyphenolic compounds, diamines, amino phenols, heterocyclic imides and amides, aliphatic diols, etc.) Pharmacokinetics of bisphenol A in neonatal and adult CD-1 mice: inter-species comparisons with Sprague-Dawley rats and rhesus monkeys. to be exposed to dangerous levels of bisphenol A epoxy diacrylate. Alternatively, bisphenol A (BPA) definition is that it is a synthetically obtained colourless crystalline organic compound that occurs in the solid phase belonging to the diphenylmethane group and is soluble in organic solvents but poorly dissolves in water (0.344 % wt. [7], BPA has been found to interact with a diverse range of hormone receptors, in both humans and animals. . [98], In all cases, wastewater treatment can be highly effective at removing BPA, giving reductions of 9198%. BPA seems to bind strongly to ERR- (dissociation constant = 5.5 nM), but only weakly to the ER. . The performance of specialized collections of bisphenol A epoxy resin system components in the evaluation of workers in an occupational health . Name: Bisphenol A epoxy diacrylate . Every day, people are exposed to a variety of activities or products that could, under certain circumstances, cause harm. The primary source of exposure to BPA for most people is through the diet. Therefore, they are effective adhesion for most substrates such as glass, ceramics, silicon wafers, and polymer materials. Bisphenol A (BPA) is a diphenylmethane derivative, commonly used in the production of polycarbonate plastics, epoxy resins, and various other plastic-based consumer products. The CLARITY Study, a 5+ year, multipronged U.S. federal government research program and the largest study ever done on BPA, confirms BPAs safety. It belongs to the phenol class of aromatic organic compounds. bisphenol a epoxy resin price are designed to form other substances and play a crucial role in numerous important reactions. Bisphenol A diglycidyl ether (DGEBA) can be called a small-molecule adhesive. 250/ Ton Get Latest Price. Pathways include photo-oxidation, or reactions with minerals such as goethite which may be present in soils and sediments. Bisphenol A (BPA) is an organic synthetic compound with the chemical formula (CH3)2C(C6H4OH)2 belonging to the group of diphenylmethane derivatives and bisphenols, with two hydroxyphenyl groups. [98] Despite its short half-life and non-bioaccumulating character, the continuous release of BPA into the environment causes continuous exposure to both plant[104] and animal life. Toxicol Appl Pharmacol. BPA is best known for its use in the manufacture of polycarbonate plastics and epoxy resins, particularly those found in water bottles, baby bottles, and other beverage and food containers. The overall health of the world economy will continue to play a major role in future demand for bisphenol A, as its derivatives' major end-use markets include automotive, construction, and electrical/electronic applications. [70][71] The body first converts it into more water-soluble compounds via glucuronidation or sulfation, which are then removed from the body through the urine. (2013) A new approach to synergize academic and guideline-compliant research: the CLARITY-BPA research program. Polyols can be compounds such as 1,4-butanediol. Before sharing sensitive information, make sure you're on a federal government site. Food cans and other metal containers may be coated with epoxy resin linings made with BPA to help prevent direct food contact with metal, which helps protect food from contamination and spoilage. Bisphenol Resin. a) Churchwell MI, Camacho L, Vanlandingham MM, Twaddle NC, Sepehr E, Delclos KB, Fisher JW, Doerge DR. The manufacturing of epoxy resins and vinyl ester resins account for 25-30% of BPA use. All rights reserved, 2,2-[(1-methylethylidene)bis(4,1-phenyleneoxymethylene)]bis[oxirane],homopoly, 4,4-(1-methylthylidene)bisphenol,polymerwith2,2-[(1-methylethylidene)bis(, Poly(Bisphenol A-co-epichlorohydrin) average Mw ~40,000, pellets, 4-(1-methylethylidene)bisphenol,-polymerwith(chloromethyl)oxirane, bis(4,1-phenyleneoxymethylene)]bis[oxirane], diglycidyletherofbisphenola-basedepoxyresins,lowmolecularweight, lowmolecularweightliquiddgebpa-basedepoxyresins, lowmolecularweightsoliddgebpa-basedepoxyresins, Phenol,4,4-(1-methylethylidene)bis-,polymerwith(chloromethyl)oxirane, phenol,4,4-isopropylidenedi-,dimerwith1-chloro-2,3-epoxypropane, phenol,4,4-isopropylidenedi-,monomerwith1-chloro-2,3-epoxypropane, phenol,4,4-isopropylidenedi-,polymerwith1-chloro-2,3-epoxypropane, phenol,4,4-isopropylidenedi-,tetramerwith1-chloro-2,3-epoxypropane, 2,2-Bis(p-hydroxyphenyl)propane-epichlorohydrin condensate, 2,2-Bis(p-hydroxyphenyl)propane-epichlorohydrin copolymer, 2,2-Bis(p-hydroxyphenyl)propane-epichlorohydrin polymer, 2,2-Diphenylolpropane-epichlorohydrin polymer, 4,4'-ISOPROPYLIDENEDIPHENOL/EPICHLOROHYDRIN COPOLYMER, 4,4-ISOPROPYLIDENEDIPHENOLEPICHLOROHYDRINRESIN, PHENOL44METHYLETHYLIDENEBISPOLYMERWITHCHLOROMETHYLOXIRANE, Reaktionsprodukt aus Bisphenol-A oder -F mit Epichlorhydrin (Molekulargewicht <700, Gehalt an freiem Epichlorhydrin <20 ppm, nicht in R40 oder R45 eingestuft), reaction product: bisphenol-A-(epichlorhydrin) epoxy resin (number average molecular weight 700), bisphenol A/ epichlorohydrin resin, solid, bisphenol A/ epichlorohydrin resin, liquid, BISPHENOL A DIGLYCIDYL ETHER RESIN structure, EPICHLOROHYDRIN-4,4'ISOPROPYLIDENEDIPHENOL RESIN, Bisphenol A epichlorohydrin polymer (25068-38-6), P201-P273-P280-P305+P351+P338-P310-P333+P313-P337+P313-P391, 36/38-43-51/53-42/43-63-62-36/37-20/21/22-45-23/24/25, BISPHENOL A DIGLYCIDYL ETHER RESIN Suppliers, BISPHENOL A DIGLYCIDYL ETHER RESIN(25068-38-6)FT-IR, TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III), 4-[1-hydroxy-2-(4-hydroxyphenyl)propan-2-yl]phenol, 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol: 2-methyloxirane, 4-[1,1,1,3,3,3-Hexafluoro-2-(4-hydroxyphenyl)propan-2-yl]phenol, Phenol, 4,4-(1-methylethylidene)bis-, polymer with (chloromethyl)oxirane, monoesters with C18-unsatd. Pharmacokinetics of bisphenol A in neonatal and adult rhesus monkeys. To improve the compatibility between flame retardant and epoxy resin (EP) matrix, amino phenyl copper phosphate-9, 10-dihydro-9-oxygen-10-phospha-phenanthrene-10-oxide (CuPPA-DOPO) is synthesized through surface grafting, which is blended with EP matrix to prepare EP/CuPPA-DOPO composites. just looking for general information about environmental health research or the institute, this page will help. It is important to note that scientific experts at FDA, and other regulatory bodies, review the full weight of the scientific evidence when making decisions about safety. [99] Regardless, the remaining 29% of BPA will continue through to the environment, with low levels of BPA commonly observed in surface water and sediment in the U.S. and Europe. NIEHS has a goal to ensure job opportunities and career enhancements programs for both our work force and our community. Get info of suppliers, manufacturers, exporters, traders of Bisphenol Resin for buying in India. resins are bisphenol A diglycidyl ether (DGEBA) and epoxy phenol BPA is used to make polycarbonate plastic and epoxy resins that are essential to a wide variety of consumer and industrial products, including many applications important to public health and food safety. [73] Concern is mostly related to its estrogen-like activity, although it can interact with other receptor systems as an endocrine-disrupting chemical. tions of epoxy resins can be preset by the chemical structure of the resin and hardener, as well as by the . Some, but not all, plastics that are marked with recycle codes 3 or 7 may be made with BPA. As can be seen from above, the product is bisphenol A diglycidyl ether when there is sufficient epichlorohydrin and enough sodium hydroxide as the catalyst. The hydroxy group may be derived from aliphatic diols, polyols (polyether polyols), phenolic compounds or dicarboxylic acids. [9][10] The remaining 5% is used as a major component of several high-performance plastics, and as a minor additive in PVC, polyurethane, thermal paper, and several other materials. . The 2003-2004 National Health and Nutrition Examination Survey (NHANES III) conducted by the Centers for Disease Control and Prevention (CDC) found detectable levels of BPA in 93% of 2517 urine samples from people six years and older. A resource for kids, parents, and teachers to find fun and educational materials related to health, science, and the environment BPA is an industrial chemical used to make a hard, clear plastic known as polycarbonate. [33] An excess of phenol is used to ensure full condensation and to limit the formation of byproducts, such as Dianin's compound. Concerns about the health effects of BPA have led some manufacturers replacing it with other bisphenols, such as bisphenol S and bisphenol F. These are produced in a similar manner to BPA, by replacing acetone with other ketones, which undergo analogous condensation reactions. [106][107] BPA appears able to effect development and reproduction in a wide range of wildlife,[107] with certain species being particularly sensitive, such as invertebrates and amphibians.[106]. Strong, shatter-resistant polycarbonate is used for helmets and protective sports visors to help protectchildren and athletes from injuries. Parents and caregivers can make the personal choice to reduce exposures of their infants and children to BPA: This content is available to use on your website. [9][10] For epoxy resin, it is first converted to its diglycidyl ether (usually abbreviated BADGE or DGEBA). BPA's largest single application is as a co-monomer in the production of polycarbonates, which accounts for 6570% of all BPA production. Table 1, Table 2 present the . The ACC mark, Responsible Care, the hands logo mark, CHEMTREC, TRANSCAER, and americanchemistry.com are registered service marks of the American Chemistry Council, Inc. May also be known as: Polycarbonate, Epoxy Resins. NIEHS is committed to conducting the most rigorous research in environmental health sciences, and to communicating the results of this research to the public. Bisphenol A (BPA) is a known endocrine disrupting chemical (EDC), and commonly used as a raw material for production of epoxy resins and polycarbonate plastics, 27 such as water bottles, tableware and food packing materials. Polycarbonate plastic is used to make hard plastic items, such as baby bottles, re-useable water bottles, food containers, pitchers, tableware and other storage containers. Some of these studies have raised questions about the safety of ingesting the low levels of BPA that can migrate into food from food contact materials. [28] BPA was never used as a drug. [65][24], As a result of the presence of BPA in plastics and other commonplace materials, most people are frequently exposed to trace levels of BPA. Published September 2022. Studying this sort of longterm, lowdose interaction is difficult, and although there have been numerous studies, there are considerable discrepancies in their conclusions regarding the nature of the effects observed as well as the levels at which they occur. 1675-54-3 Chemical Name: BISPHENOL A DIGLYCIDYL ETHER RESIN CBNumber: CB3749115 Molecular Formula: C21H24O4 Molecular Weight: 340.41 MDL Number: MFCD00080480 MOL File: 1675-54-3.mol MSDS File: SDS Modify Date: 2022-12-30 16:20:48 Request For Quotation BISPHENOL A DIGLYCIDYL ETHER RESIN Properties SAFETY FDA can take this action on its own initiative or in response to a food additive petition that demonstrates that a use of a food additive has been permanently and completely abandoned. [90] It can also protect it from deactivation from the SERM 4-hydroxytamoxifen (afimoxifene). Some of this is further reacted with methacrylic acid to form bis-GMA, which is used to make vinyl ester resins. The chemical formula is (CH 3 ) 2 C(C 6 H 4 OH) 2. This search feature obtains best-matches with the terms you choose, and shows an overall score based on the scientific rankings. Bisphenol A (BPA), a colourless crystalline solid belonging to the family of organic compounds; its molecular formula is C 15 H 16 O 2.BPA is best known for its use in the manufacture of polycarbonate plastics and epoxy resins, particularly those found in water bottles, baby bottles, and other beverage and food containers. . MATERIAL SAFETY DATA SHEET West System Inc. MSDS #105-13a Last Revised: 26APR13 1. Bisphenol F (BPF) based epoxy resins are more flexible than that of BPA-based epoxies. Chemical Name: Hydrogenated Bisphenol A Epoxy Resin CAS No. Advantage Description. Explore thermosetting epoxy resins in detail along with their key properties and understand what makes them an ideal choice in so many applications. [91], BPA has been detectable in the natural environment since the 1990s and is now widely distributed. Bisphenol A (BPA) is a chemical compound primarily used in the manufacturing of various plastics. The CLARITY Study, the largest study ever done on BPA and conducted by FDA experts, confirms that BPA is safe, and supports the agencys one word answer to the question: Is BPA safe?: Yes. The original approvals for BPA were issued under FDAs food additive regulations and date from the 1960s. FDA continues to review the available information and studies on BPA. While they have high mechanical strength values similar to epoxy resins, they are easy to apply similar to unsaturated polyester resins. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. BPA is one of the most thoroughly tested chemicals in use today and has a safety track record of more than 50 years. When possible, opt for glass, porcelain or stainless steel containers, particularly for hot food or liquids. Products made from BPA meet high-performance demands. Bisphenol S (BPS) is an organic compound with the formula (HOC 6 H 4) 2 SO 2.It has two phenol functional groups on either side of a sulfonyl group. mixing process is what I used. CHEMICAL PRODUCT AND COMPANY IDENTIFICATION PRODUCT NAME:WEST SYSTEM 105 Epoxy Resin Epoxy resin is a polymer with the molecular formula (C11H12O3)n, which is a general term for a class of polymers containing more than two epoxy groups in the molecule. Formula: CAS CAS: Chemical Abstract Service Registry Number . It is alcohol, ketone and ether soluble but presents low solubility in water and carbon tetrachloride. If you are giving a presentation about an environmental health topic or Visit ChemicalBook To find more Bisphenol A epoxy resin() information like chemical properties,Structure,melting point,boiling point,density,molecular formula,molecular weight, physical properties,toxicity information,customs codes. The synthesis of diglycidyl ether of bisphenol A (DGEBA), the most widely used epoxy resin monomer, is: Rapid Commun Mass Spectrom. 2012 May-Jun;34(3):331-7. l) Patterson TA, Twaddle NC, Roegge CS, Callicott RJ, Fisher JW, Doerge DR. Concurrent determination of bisphenol A pharmacokinetics in maternal and fetal rhesus monkeys. [7] As the only by-product is water, it may be considered an industrial example of green chemistry. Pharmacokinetics of bisphenol A in serum and adipose tissue following intravenous administration to adult female CD-1 mice. The safety of a food additive is not relevant to FDAs determination regarding whether a certain use of that food additive has been abandoned. Find here online price details of companies selling Bisphenol Resin. 12 oz. 2010 Oct 30;24(20):3011-20. n) Yang X, Doerge DR, Fisher JW. Epoxy resins produced from such epoxy monomers are called glycidyl-based epoxy resins. This orphan receptor (endogenous ligand unknown) behaves as a constitutive activator of transcription. Phenol-formaldehyde resin . Distillation and vacuum distillation are used to remove toluene and unreacted epichlorohydrin, respectively. The FDA review has not found any information in the evaluated studies to prompt a revision of FDAs safety assessment of BPA in food packaging at this time. The subchronic study was designed to characterize potential effects of BPA in a wide range of endpoints, including prostate and mammary glands, metabolic changes, and cardiovascular endpoints. Due to its especially thick natural consistency, there will commonly be additives and diluents which are added into the Bisphenol-A epoxy formula to enhance workability and adhesion. Pharmacokinetics of bisphenol A in neonatal and adult Sprague-Dawley rats. Some animal studies suggest that infants and children may be the most vulnerable to the effects of BPA. In particular, infants are considered to be at greater risk,[83] leading to bans on the use of BPA in baby bottles and related products by the US,[84] Canada,[85] and EU[86] amongst others. Bisphenol A | C15H16O2 | CID 6623 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. [74] It binds to both of the nuclear estrogen receptors (ERs), ER and ER. Bisphenol A diglycidyl ether (DGEBA) is a pale yellow liquid epoxy compound formed by the polycondensation of epichlorohydrin (ECH) and bisphenol A (BPA). Furthermore, composite . [95] Many of the largest sources of BPA pollution are water-based, particularly wastewater from industrial facilities using BPA. About 6570% of all bisphenol A is used to make polycarbonate plastics,[9][10] which can consists of nearly 90% BPA by mass.

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